To start an e-commerce business, consider selling niche, trending, or high-profit-margin products that cater to specific audiences, like eco-friendly items, personalized gifts, or smart gadgets. Health and wellness products, subscription-based items, and problem-solving tools like ergonomic office accessories or time-saving kitchen gadgets also perform well. Evergreen products such as home essentials and electronics accessories provide steady demand, while handmade or local goods add uniqueness to your offerings. Prioritize products with consistent demand, manageable competition, and the potential for strong branding, ensuring you validate your ideas with market research before scaling up.